The spectral manifistation of the new luminescent styryl dyes photostability and phototoxic influence on the DNA

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dc.contributor.authorKudrya, V.
dc.contributor.authorYashchuk, V.
dc.contributor.authorGusak, V. V.
dc.contributor.authorLosytskyy, M.
dc.contributor.authorKryvorotenko, D.
dc.contributor.authorBalanda, A.
dc.contributor.authorYarmoluk, S.
dc.contributor.authorGumenjuk, Y.
dc.date.accessioned2015-12-22T13:33:17Z
dc.date.available2015-12-22T13:33:17Z
dc.date.issued2006
dc.description.abstractThe spectral investigation methods of the phenomena of luminescent dye probes photostability and phototoxic influence on the DNA were proposed. The optical absorption, fluorescence and phosphorescence spectra of the samples of the newest investigated styryl dyes and the systems DNA +dye were studied. The optical absorption spectra of the samples of these compounds were measured under the irradiation of these samples by visible light. The results of the investigations carried out on a number of dyes were analyzed and discussed. The changes of optical density D value in wavelength regions 250+300 nm (that corresponds to the DNA first electronic transition) and 370+650 nm (that corresponds to a dye electronic transition) of the DNA+dye solutions were fixed. The dynamics ofD(t) was not monotonous. It was shown the Mn-Styr and Di-Styr-30 dyes are photochemically safe for the DNA; these dyes bound to the DNA are more photostable than in free state. The Di-Styr-24 and Dst-MdO dyes show slight phototoxic effect on the DNA. The versions of possible phototoxicity (and photostability) mechanisms are proposed.en
dc.identifier.citationThe spectral manifistation of the new luminescent styryl dyes photostability and phototoxic influence on the DNA/ V. Yu. Kudrya, V. M. Yashchuk, V. V. Gusak, M. Yu. Losytskyy, D. V. Kryvorotenko, A. O. Balanda, S. M. Yarmoluk, Ya. O. Gumenjuk // Наукові записки НаУКМА. - 2006. - Т. 51 : Фізико-математичні науки. - С. 35-42.uk
dc.identifier.urihttps://ekmair.ukma.edu.ua/handle/123456789/7604
dc.language.isoukuk
dc.statuspublished earlieruk
dc.subjectluminescent dyesuk
dc.subjectphototoxicity for the DNAuk
dc.subjectphotostabilityuk
dc.subjectoptical absorption spectrumuk
dc.subjectметоди спектральних дослідженьuk
dc.subjectфотостабільністьuk
dc.subjectДНКuk
dc.subjectфототоксичний впливuk
dc.titleThe spectral manifistation of the new luminescent styryl dyes photostability and phototoxic influence on the DNAen
dc.typeArticleuk
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