Evaluation of Efficiency of SPR-Based Biosensor and ZnO Photoluminescent Biosensor ib the Anlysys of Biogenic Polyamines
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Date
2020
Authors
Prylutskyi, Maksym
Starodub, Nickolaj
Taran, O.
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Abstract
In this research it was demonstrated the efficiency of the
biosensors based on the different principles at the detection of the
biogenic amines which are as informative elements at the diagnostic of
the cancer events including development of the breast cancer. It was
compared two type of the optical devices namely based on the surface
plasmon resonance (SPR) and on the photoluminescence of the ZnO
nanostructures. Both types of the biosensors could able to detect such low molecular agents
as polyamines in model solution at the concentration from 10 to 100 ng/ml. Nevertheless
SPR-based biosensor showed better results than ZnO biosensor at the detecting as low and
high concentrations of polyamines. In particular, the differences in the analyse efficiency at
the determination of the above indicated concentrations between the used biosensors was in
range from 14% to 30%. In spite of this data it was demonstrated that ZnO biosensor also
may be used for estimation of level of polyamines at the cancer diagnostics.
Description
Keywords
Biosensors, SPR, zinc oxide, photoluminescence, polyamines, article
Citation
Prilutskiy M. P. Evaluation of Efficiency of SPR-Based Biosensor and ZnO Photoluminescent Biosensor ib the Anlysys of Biogenic Polyamines / M. P. Prilutskiy, N. F. Starodub and O. P. Taran // World Journal of Engineering Research and Technology. - 2020. - Vol. 6, Issue 6. - P. 230-237.