Determination of the Concentration of Polyamines with SPR-based Immune Biosensor for Early Diagnostics of Breast Cancer

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dc.contributor.authorPrylutskyi, Maksym
dc.contributor.authorStarodub, Nickolaj
dc.contributor.authorBilko, Nadiia
dc.date.accessioned2017-05-27T14:41:35Z
dc.date.available2017-05-27T14:41:35Z
dc.date.issued2016
dc.description.abstractThe paper presents the results of research on the development of immune biosensor test system for express detection of polyamines in cells of breast cancer. Determination of polyamines was performed by using an analytical device - immune biosensor based on surface plasmon resonance (SPR), where "antigen-antibody" reaction is performed in real time on the surface of transducer, resulting in formation of immune complexes and recording the shift of resonance angle. The method can detect the studied polyamines spermine and spermidine in concentration less than ’0 ng in ’ mL, and with increasing concentrations a statistical probability of the analysis' result rise sharply. Moreover, the dependence of sensitivity of biosensor response from the concentration of polyamines is in the range of ’0-’00 ng /mL.en
dc.identifier.citationPrylutskyi M. Determination of the Concentration of Polyamines with SPR-based Immune Biosensor for Early Diagnostics of Breast Cancer [electronic resource] / Prylutskyi M., Starodub N., Bilko N. // Journal of Biosensors & Bioelectronics. - 2016. - Vol. 7, Issue 4. - 7 p. - Метод доступу: Інтернет. - DOI: 10.4172/2155-6210.1000227 (переглянуто 26 травня 2017 р.). - Назва з екрана.uk
dc.identifier.urihttps://ekmair.ukma.edu.ua/handle/123456789/11418
dc.language.isoenuk
dc.relation.sourceJournal of Biosensors & Bioelectronicsuk
dc.statuspublished earlieren
dc.subjectPolyaminesen
dc.subjectAntibodyen
dc.subjectAntigenen
dc.subjectSurface plasmon resonanceen
dc.subjectBreast canceren
dc.titleDetermination of the Concentration of Polyamines with SPR-based Immune Biosensor for Early Diagnostics of Breast Canceren
dc.typeArticleuk
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