Epitopes identification of broadly neutralizing monoclonal antibodies against Corynebacterium diphtheriae exotoxin

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dc.contributor.authorKulyk, Ya.
dc.contributor.authorSiromolot, Andriy
dc.contributor.authorKolybo, Denys
dc.date.accessioned2023-04-19T09:21:27Z
dc.date.available2023-04-19T09:21:27Z
dc.date.issued2022
dc.description.abstractBetter and high-potency vaccines against diphtheria are urgently needed to provide broader protection against diverse strains and subtypes. Identification of novel broadly neutralizing epitopes targeted by protective antibodies could aid in such efforts. Aim. In this study we focused on the search of binding sites identification of anti diphtheria toxin monoclonal antibodies and their neutralizing activity to block binding of recombinant exotoxin derivates with host receptors.en_US
dc.identifier.citationKulyk Ya. S. Epitopes identification of broadly neutralizing monoclonal antibodies against Corynebacterium diphtheriae exotoxin / Kulyk Ya. S., Siromolot A. A., Kolybo D. V. // Biotechnologia Acta. - 2022. - Vol. 15, No. 4. - P. 37-40. - https://doi.org/10.15407/biotech15.04.037en_US
dc.identifier.issn2410-7751
dc.identifier.issn2410-776X
dc.identifier.urihttps://ekmair.ukma.edu.ua/handle/123456789/25065
dc.identifier.urihttps://doi.org/10.15407/biotech15.04.037
dc.language.isoen
dc.relation.sourceBiotechnologia actaen_US
dc.statusfirst publisheden_US
dc.subjectdiphtheria toxinen_US
dc.subjectCRM197en_US
dc.subjectSbBen_US
dc.subjectmonoclonal antibodiesen_US
dc.subjectproHB-EGFen_US
dc.subjectepitopes mappingen_US
dc.subjectneutralizing antibodyen_US
dc.subjectarticleen_US
dc.titleEpitopes identification of broadly neutralizing monoclonal antibodies against Corynebacterium diphtheriae exotoxinen_US
dc.typeArticleen_US
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