Bespalko, OleksandrVakuliuk, PolinaFurtat, IrynaPryshchepa, OleksandraKozakevych, RomanPomastowskі, Paweł2025-09-222025-09-222025Antibacterial properties of composite materials based on metal/metal-oxide nanoparticles, nanosilica and polylactid acid / Bespalko O. V., Vakuliuk P. V., Furtat I. M., Pryshchepa O., Kozakevych R. B., Pomastowski P. // The International research and practice conference "Nanotechnology and nanomaterials" (NANO-2025) : abstract book of participants of the International research and practice conference, 20–23 August 2025, Bukovel / edited by Olena Fesenko ; Technology transfer Department of Institute of Physics of NAS of Ukraine. - Kyiv, 2025. - P. 209.https://ekmair.ukma.edu.ua/handle/123456789/36755The global rise in antimicrobial resistance necessitates the development of alternative materials with effective antibacterial properties. This study compares two classes of nanocomposites: silver nanoparticle (AgNP)- and zinc oxide (ZnO)-based systems, both immobilized on silica (SiO₂) and treated with polylactic acid (PLA) to enhance biocompatibility and biodegradability. AgNP-containing composites (SiO₂- Ag and SiO₂-Ag-PLA) exhibited potent, broad-spectrum antibacterial activity, particularly against Gram-negative E. coli and K. pneumoniae, though activity decreased when modified with PLA—likely due to reduced ion release and surface coverage interference.enantimicrobial resistancenanocompositesAg-based compositesconference materialsConference materials